Serene by Nature Mare Calming Cream 2oz

(1 customer review)


Serene by Nature topical cream promotes mare calmness and focus.

  • One 2 oz tube lasts approximately 3-4 weeks.
  • Easy topical application.
  • Bio-identical, safe, natural, and effective.
  • Veterinarian tested, approved, and recommended.
  • USEF and FEI compliant.
  • No known negative side effects or drug interactions.
  • Safe alternative to synthetic drugs.
  • Includes Free Gloves for application.

Serene by Nature cream is a safe, effective, natural, and USEF and FEI compliant topical cream that helps support a healthy endocrine system for calmer and more focused mares (may be used on non-cycling equines as well).


SKU: mcc1-1 Category: Tag:


Serene by Nature topical cream

is specifically formulated to decrease irritability and improve attitude in nervous and cranky mares. Serene by Nature topical cream may be beneficial in dealing with the cyclical changes all mares experience. Reproductive health may be improved by supporting the endocrine system via a normal healthy balance.

Providing natural endocrine support may help to improve daily demeanor, focus, trainability, and overall well-being.

This product may be beneficial for:

  • Helping to maintain a calm and serene disposition on a daily basis.
  • Ease and regularity of seasonal cycles.
  • Supporting a healthy reproductive system.




Additional information

Weight 0.2 lbs
Dimensions 4 × 1.25 × 4 in
Free Glove Size

Medium, Large

1 review for Serene by Nature Mare Calming Cream 2oz

  1. CookCathy

    If you haven’t used Serene by Nature yet, this is a GREAT way to try it. Smaller portion, and cheaper, so you can order without spending much, although they do offer a 30 day money back guarantee.

    I have been using Serene for about 1 1/2 years now, and I am a firm believer in this product. My mare went from being very spooky, unfocused, tense, to much more focused, more calm and eliminated any screaming when she was separated from her next door neighbor gelding.

    (No one wants to hear that).

    I have used other “calming” products, and I also use “Via-Calm” which is a magnesium product, but it does not address the “screaming” issue, or the focus.

    TRY this product. I was skeptical, but I was given a tube from a friend and I tried it. The results showed in a matter of just a couple of days.

    I love that it is all natural as well. Depo works, and you will pay $80 bucks a shot, and they may be necessary every two weeks. Not only can I not afford that, but I would never want my mare on a hormone.

    My background? Trainer for 30 years, and I have never used any calming products, but this mare really needed something. I was getting very frustrated and at one point, or several points, even considered re-homing her.

    So, we are happy, calm, less spooky and far less hormonal………. Thank you Serene by Nature!

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